Tussionex PennKinetic



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Accepted at over 60,000 pharmacies nationwide

Generic Name: chlorpheniramine and hydrocodone
(KLOR fen IR a meen and HYE droe KOE done)

What is Tussionex PennKinetic?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Hydrocodone is a narcotic cough suppressant.

The combination of Tussionex PennKinetic is used to treat runny or stuffy nose, sneezing, and cough caused by the common cold or flu.

Tussionex PennKinetic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Tussionex PennKinetic?

Do not take this medication more often than prescribed. An overdose of Tussionex PennKinetic can cause life-threatening side effects.

To be sure you get the correct dose, measure this medicine carefully with a marked measuring spoon or syringe, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Before you take Tussionex PennKinetic, tell your doctor if you have asthma or another breathing disorder, a history of head injury or brain tumor, stomach or intestinal problems, liver or kidney disease, glaucoma, urination problems or an enlarged prostate, Addison's disease, or underactive thyroid.

Tussionex PennKinetic can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while using Tussionex PennKinetic. Alcohol may increase drowsiness and dizziness.

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Do not give this medicine to a child younger than 6 years old.

What should I discuss with my healthcare provider before taking Tussionex PennKinetic?

You should not take this medication if you are allergic to chlorpheniramine or hydrocodone.

Before taking Tussionex PennKinetic, tell your doctor if you are allergic to any drugs, or if you have:

  • asthma or other breathing disorder
  • a history of head injury or brain tumor
  • stomach or intestinal problems
  • liver or kidney disease
  • glaucoma
  • urination problems or an enlarged prostate
  • Addison's disease; or
  • underactive thyroid.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. Tussionex PennKinetic may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether Tussionex PennKinetic passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medicine.

Do not give Tussionex PennKinetic to a child younger than 6 years old.

How should I take Tussionex PennKinetic?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Do not take this medication more often than you doctor has prescribed. An overdose of Tussionex PennKinetic can cause life-threatening side effects.

Shake the oral solution (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid carefully with a marked measuring spoon or syringe, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not mix this medicine with any other liquid before taking it.

Tussionex PennKinetic can be taken with food if it upsets your stomach.

Store Tussionex PennKinetic at room temperature away from moisture and heat.

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Tussionex PennKinetic can be fatal, especially to a child.

Overdose symptoms may include dry mouth, cold and clammy skin, flushing, large pupils, nausea, vomiting, severe dizziness or drowsiness, seizure (convulsions), shallow breathing, slow heart rate, blue colored skin, feeling light-headed, or fainting.

What should I avoid while taking Tussionex PennKinetic?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol while using Tussionex PennKinetic. Alcohol may increase drowsiness and dizziness.

What are the possible side effects of Tussionex PennKinetic?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • weak or shallow breathing
  • chest tightness
  • painful urination
  • urinating less than usual or not at all; or
  • confusion, hallucinations, or unusual behavior.

Less serious side effects may include:

  • dizziness, drowsiness, trouble concentrating
  • mood changes, anxiety
  • blurred vision
  • constipation, nausea, vomiting, loss of appetite
  • dry mouth or throat
  • sweating; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tussionex PennKinetic?

Narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by Tussionex PennKinetic. Tell your doctor if you regularly use any of these medicines, or any other cold or allergy medicine.

Tell your doctor about all other medications you use, especially:

  • atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop)
  • bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva)
  • glycopyrrolate (Robinul)
  • mepenzolate (Cantil)
  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine); or
  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).

This list is not complete and there may be other drugs that can interact with Tussionex PennKinetic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about Tussionex PennKinetic.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.