Timentin
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Generic Name: ticarcillin and clavulanate potassium (injection)
(TYE kar SIL in KLAV ue la nate poe TAS ee um)
What is Timentin?
Ticarcillin is an antibiotic in a group of drugs called penicillins. Ticarcillin fights bacteria in the body.
Clavulanate potassium is a form of clavulanic acid, which is similar to penicillin. Clavulanate potassium fights bacteria that is often resistant to penicillins and other antibiotics.
The combination of Timentin is used to treat many different infections caused by bacteria, such as urinary tract infections, bone and joint infections, severe vaginal infections, stomach infections, and skin infections.
Timentin may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about Timentin?
Do not use this medication if you are allergic to clavulanate potassium, ticarcillin or to any other penicillin antibiotic, such as amoxicillin (Amoxil, Augmentin), ampicillin (Omnipen, Principen), carbenicillin (Geocillin), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.
Before using Timentin tell your doctor if you are allergic to cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others, or if you have kidney disease, a bleeding or blood clotting disorder, low levels of potassium in your blood, a history of any type of allergy, or if you are on a salt-restricted diet.
Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Timentin will not treat a viral infection such as the common cold or flu.
Timentin can make birth control pills less effective. Use a second non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while using ticarcillin and clavulanate potassium.
What should I discuss with my healthcare provider before using Timentin?
Do not use this medication if you are allergic to clavulanate potassium, ticarcillin, or to any other penicillin antibiotic, such as:
- amoxicillin (Amoxil, Augmentin)
- ampicillin (Omnipen, Principen)
- carbenicillin (Geocillin)
- dicloxacillin (Dycill, Dynapen)
- oxacillin (Bactocill); or
- penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others).
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using Timentin, tell your doctor if you are allergic to any drugs (especially cephalosporins such as Ceclor, Ceftin, Duricef, Keflex, and others), or if you have:
- kidney disease
- a bleeding or blood clotting disorder
- an electrolyte imbalance such as low levels of potassium in your blood
- a history of any type of allergy; or
- if you are on a salt-restricted diet.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Timentin can make birth control pills less effective. Use a second non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while using ticarcillin and clavulanate potassium.
It is not known whether Timentin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I use Timentin?
Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.
Timentin is given as an injection through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to use your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.
Timentin must be mixed with a liquid (diluent) before injecting it. Do not mix the medicine until you are ready to give yourself an injection.
Timentin is usually given for 10 to 14 days, depending on the infection being treated. Follow your doctor's instructions.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
Use this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Timentin will not treat a viral infection such as the common cold or flu.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using Timentin.
Store unmixed Timentin, and the liquid diluent, at cool room temperature.
What happens if I miss a dose?
Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include drowsiness, hyperactivity, or seizure (convulsions).
What should I avoid while using Timentin?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
What are the possible side effects of Timentin?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- diarrhea that is watery or bloody
- blood in your urine, feeling an urgent need to urinate, painful or difficult urination
- easy bruising or bleeding, unusual weakness
- dry mouth, increased thirst, confusion, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting
- fever, chills, body aches, flu symptoms
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash
- chest pain; or
- seizure (convulsions).
Less serious side effects may include:
- mild diarrhea, gas, stomach pain
- nausea or vomiting
- joint or muscle pain
- headache
- skin rash or itching;
- pain, swelling, or burning where the injection was given; or
- vaginal yeast infection (itching or discharge).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Timentin?
There may be other drugs that can affect Timentin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about ticarcillin and clavulanate.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are using, check with your doctor, nurse or pharmacist.
Copyright 1996-2009 Cerner Multum, Inc. Version: 1.05. Revision Date: 4/12/2009.
