Sytobex


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Generic Name: cyanocobalamin (oral)
(sye AN oh koe BAL a min)

What is the most important information I should know about oral Sytobex?

You should not use this medication if you are allergic to cobalt, or if you have Leber's disease. Sytobex can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.

To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life.Not using the medication can lead to irreversible nerve damage in your spinal cord.

Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Take all of your medications as directed.

Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.

What is oral Sytobex?

Sytobex is a man-made form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.

Sytobex is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions.

Sytobex may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking oral Sytobex?

You should not use this medication if you are allergic to cobalt, or if you have Leber's disease. Sytobex can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take oral Sytobex:

  • any type of infection
  • iron or folic acid deficiency
  • kidney or liver disease; or
  • if you are receiving any medication or treatment that affects bone marrow.

FDA pregnancy category C. It is not known whether Sytobex can harm an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

Sytobex passes into breast milk, but it is not known whether cyanocobalamin could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take oral Sytobex?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.

Take oral Sytobex with a full glass of water.

The sublingual tablet should be placed under your tongue where it will dissolve.

Do not crush, chew, break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

To be sure this medication is helping your condition, your blood will need to be tested every 3 to 6 months. This will help your doctor determine the correct dose and how long to treat you with Sytobex. Do not miss any scheduled appointments.

To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life.Not using the medication can lead to irreversible nerve damage in your spinal cord.

Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Take all of your medications as directed.

Store this medication at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do nottake extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Sytobex is not likely to cause life-threatening symptoms.

What should I avoid while taking oral Sytobex?

Avoid drinking large amounts of alcohol while you are being treated with Sytobex.

What are the possible side effects of oral Sytobex?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • chest pain
  • feeling short of breath, even with mild exertion
  • swelling, rapid weight gain; or
  • unusual warmth, redness, or pain in an arm or leg.

Less serious side effects may include:

  • headache, dizziness, weakness
  • nausea, upset stomach, diarrhea
  • numbness or tingling
  • fever
  • joint pain
  • swollen tongue
  • swelling; or
  • itching or rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect oral Sytobex?

Before taking Sytobex, tell your doctor if you are taking any of the following medications:

  • antibiotics
  • methotrexate (Rheumatrex)
  • pyrimethamine (Daraprim)
  • colchicine; or
  • if you drank a lot of alcohol within the past 2 weeks.

This list is not complete and there may be other drugs that can interact with Sytobex. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about oral Sytobex.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2009 Cerner Multum, Inc. Version: 5.01. Revision date: 04/21/2009.