Panretin
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Generic Name: alitretinoin topical
(ah lih TREH tin oyn)
What is Panretin?
Alitretinoin is a topical retinoid. Alitretinoin affects the growth and development of skin cells.
Panretin is used to treat skin lesions caused by AIDS-related Kaposi's sarcoma.
Panretin may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Panretin?
Avoid prolonged exposure to sunlight. Panretin may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
Do not use products that contain DEET (N, N-diethyl-m-toluamide), a common component of insect repellent products, while using Panretin. There is an increased risk of harmful effects from DEET when it is used with alitretinoin topical.
Do not cover the treated lesions with any type of occlusive dressing (a dressing that does not allow air to circulate to the area).
Who should not use Panretin?
Before using Panretin, tell your doctor if you have cutaneous T-cell lymphoma. You may not be able to use alitretinoin topical, or you may require a dosage adjustment or special monitoring during your treatment.
Panretin is the FDA pregnancy category D. This means that alitretinoin topical may be harmful to an unborn baby. Alitretinoin topical has caused birth defects in animal studies. Do not use alitretinoin topical without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether Panretin passes into breast milk. Do not use alitretinoin topical without first talking to your doctor if you are breast-feeding a baby.
How should I use Panretin?
Use Panretin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Wash your hands before and after applying this medication.
Apply enough gel to cover the lesion with a generous coating. Allow the gel to dry for 3 to 5 minutes before covering the area with clothing.
Do not apply Panretin to normal skin surrounding a lesion. Also, do not apply alitretinoin topical on or near mucosal surfaces of the body such as the inside of the nose or mouth.
Do not cover the treated lesions with any type of occlusive dressing (a dressing that does not allow air to circulate to the area).
Panretin is usually applied two to four times a day. Follow your doctor's instructions.
Store Panretin at room temperature away from moisture and heat.
What happens if I miss a dose?
Apply the missed dose as soon as you remember.
What happens if I overdose?
An overdose of this medication is unlikely to occur. If you do suspect an overdose, or if Panretin has been ingested, call an emergency room or poison control center for advice.
What should I avoid while using Panretin?
Avoid prolonged exposure to sunlight. Panretin may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
Do not use products that contain DEET (N, N-diethyl-m-toluamide), a common component of insect repellent products, while using Panretin. There is an increased risk of harmful effects from DEET when it is used with alitretinoin topical.
Do not cover the treated lesions with any type of occlusive dressing (a dressing that does not allow air to circulate to the area).
What are the possible side effects of Panretin?
Serious side effects are not likely to occur. Stop using Panretin and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).
If you experience any of the following less serious side effects at the application site(s), continue to use Panretin and notify your doctor
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Panretin?
Do not use products that contain DEET (N, N-diethyl-m-toluamide), a common component of insect repellent products, while using Panretin. There is an increased risk of harmful effects from DEET when it is used with alitretinoin topical.
Drugs other than those listed here may also interact with Panretin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
Your pharmacist has additional information about Panretin written for health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2009 Cerner Multum, Inc. Version: 2.04. Revision Date: 4/12/2009.
