Oxytrol



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Generic Name: oxybutynin (oral)
(OX i BUE ti nin)

What is Oxytrol?

Oxytrol reduces muscle spasms of the bladder and urinary tract.

Oxytrol is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.

Oxytrol may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Oxytrol?

You should not use this medication if you are allergic to Oxytrol, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

Before using Oxytrol, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxytrol can decrease perspiration and you may be more prone to heat stroke.

Oxytrol can cause side effects that may impair your vision or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

There are many other medicines that can interact with Oxytrol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.

What should I discuss with my healthcare provider before using Oxytrol?

Do not use this medication if you are allergic to Oxytrol, or if you have:

  • untreated or uncontrolled glaucoma
  • a blockage in your digestive tract (stomach or intestines); or
  • if you are unable to urinate.

If you have certain conditions, you may need a dose adjustment or special tests to safely take this medication. Before taking Oxytrol, tell your doctor if you have:

  • glaucoma
  • liver disease
  • kidney disease
  • an enlarged prostate
  • ulcerative colitis
  • a blockage in your stomach or intestines;
  • a muscle disorder such as myasthenia gravis; or
  • a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether Oxytrol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Oxytrol?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medication with a full glass of water.

Oxytrol may be taken with or without food.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Oxytrol with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Try to take this medication at the same time each day.

If you use the extended-release form of Oxytrol, you may notice what looks like part of a tablet in your stools. The tablet shell is not designed to be absorbed by the body, and may therefore pass into the stools without dissolving. This is a normal side effect of oxybutynin extended-release tablets.

Store Oxytrol at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include restlessness, tingly feeling, fever, uneven heart rate, vomiting, and urinating less than usual or not at all.

What should I avoid while using Oxytrol?

Oxytrol can cause blurred vision, drowsiness, or dizziness. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxytrol can decrease perspiration and you may be more prone to heat stroke.

What are the possible side effects of Oxytrol?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Oxytrol and call your doctor at once if you have any of these serious side effects:

  • hot, dry skin and extreme thirst
  • severe stomach pain or constipation
  • pain or burning when you urinate; or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • dry mouth
  • dry eyes, blurred vision
  • mild constipation
  • diarrhea
  • nausea, mild stomach pain or upset
  • dizziness, drowsiness, weakness
  • headache;
  • sleep problems; or
  • runny nose.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Oxytrol?

The following drugs can interact with Oxytrol. Tell your doctor if you are using any of these:

  • other bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), tolterodine (Detrol), or solifenacin (Vesicare)
  • glycopyrrolate (Robinul)
  • flecainide (Tambocor)
  • mepenzolate (Cantil)
  • thioridazine (Mellaril)
  • HIV /AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir)
  • an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), or troleandomycin (Tao)
  • an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral)
  • atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop)
  • bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva)
  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine); or
  • an antidepressant such as amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), and others.

This list is not complete and there are many other drugs that can interact with Oxytrol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about Oxytrol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.