Glyset


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Accepted at over 60,000 pharmacies nationwide

Generic Name: miglitol
(MIG lih tall)

What is Glyset?

Glyset delays the digestion of carbohydrates (forms of sugar) in your body. This decreases the amount of sugar that passes into your blood after a meal and prevents periods of hyperglycemia (high blood sugar).

Glyset is used to treat non-insulin-dependent (Type II) diabetes mellitus.

Glyset may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Glyset?

Take each dose of Glyset with the first bite of a main meal.

Know the signs and symptoms of low blood sugar, which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and, nausea. Carry glucose tablets, paste, or another glucose or dextrose substance to treat episodes of low blood sugar.

Who should not take Glyset?

Before taking this medication, tell your doctor if you have

  • an inflammatory bowel disease, such as ulcerative colitis or Chron's disease; or any other disease of the stomach or intestines
  • ulcers of the colon
  • a blockage or obstruction in your intestines; or
  • kidney disease.

    • You may not be able to take Glyset, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

    Call your doctor if you develop a fever or an infection, or if you experience a serious injury. You may require insulin for a period of time to control your blood sugar levels.

    Glyset is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take miglitol without first talking to your doctor if you are pregnant.

    Glyset passes into breast milk and may affect a nursing infant. Do not take miglitol without first talking to your doctor if you are breast-feeding a baby.

    How should I take Glyset?

    Take Glyset exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

    Take each dose with a full glass of water.

    Take each dose with the first bite of a main meal.

    Store Glyset at room temperature away from moisture and heat.

    What happens if I miss a dose?

    Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

    What happens if I overdose?

    Seek emergency medical attention.

    An overdose of this medication is unlikely to occur. Symptoms of an overdose are unknown, but stomach pain, gas, bloating, and diarrhea might be expected.

    What should I avoid while taking Glyset?

    Follow your doctor's diet and exercise recommendations to help control your blood sugar levels.

    Use alcohol cautiously. Alcohol may affect your blood sugar levels.

    What are the possible side effects of Glyset?

    Stop taking Glyset and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

    Other, less serious side effects, are more likely to occur. Continue to take Glyset and talk to your doctor if you experience

  • abdominal pain,
  • diarrhea,
  • flatulence, or
  • a rash.

    • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

    What other drugs will affect Glyset?

    Digestive-enzyme supplements such as pancreatin (amylase, protease, lipase) in products such as Arco-Lase, Cotazym, Donnazyme, Pancrease, Creon, Ku-Zyme, and others may decrease the effects of Glyset. These medications should not be taken at the same time as miglitol.

    Before taking this medication, tell your doctor if you are taking any of the following medicines:

    • propranolol (Inderal)
    • ranitidine (Zantac, Zantac 75)
    • digoxin (Lanoxin, Lanoxicaps),
    • another diabetes medicine such as glyburide (Micronase, Diabeta, Glynase), glipizide (Glucotrol), tolbutamide (Orinase), metformin (Glucophage), and others
    • a thiazide diuretic (water pill) such as hydrochlorothiazide (HCTZ, Hydrodiuril, others), chlorothiazide (Diuril), chlorthalidone (Thalitone), indapamide (Lozol), and others
    • a steroid medication such as prednisone (Deltasone), methylprednisolone (Medrol), and others
    • an estrogen (Premarin, Ogen, and others) or an estrogen-containing birth control pill
    • a thyroid medication (Synthroid, Levoxyl, and others)
    • phenytoin (Dilantin); or
    • a calcium channel blocker such as verapamil (Calan, Verelan, Isoptin), diltiazem (Cardizem, Dilacor XR), nifedipine (Procardia, Adalat), and others.

    The drugs listed above may interact with Glyset or affect blood sugar levels. You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

    Drugs other than those listed here may also interact with Glyset or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

    Where can I get more information?

    Your pharmacist has more information about Glyset written for health professionals that you may read.

    Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

    Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Copyright 1996-2009 Cerner Multum, Inc. Version: 1.04. Revision Date: 4/12/2009.