COPD



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Generic Name: dyphylline and guaifenesin
(DYE fil in and gwye FEN e sin)

What is COPD?

Dyphylline is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

The combination of COPD is used to treat cough and breathing problems caused by bronchial asthma, chronic bronchitis, or emphysema. This medication is not a cure for asthma, bronchitis, or emphysema.

COPD may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about dyphylline and COPD?

You should not use this medicine if you are allergic to dyphylline or guaifenesin. This medication will not treat an asthma attack.

Before taking this medication, tell your doctor if you have heart disease or a history of heart attack, high blood pressure, overactive thyroid, or a stomach ulcer.

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Always ask a doctor before giving cough or cold medicine to a child.Death can occur from the misuse of cough or cold medicine in very young children.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. Guaifenesin is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much guaifenesin. Read the label of any other medicine you are using to see if it contains guaifenesin.

What should I discuss with my healthcare provider before taking COPD?

You should not use this medicine if you are allergic to dyphylline or guaifenesin. This medication will not treat an asthma attack.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take COPD, tell your doctor if you have:

  • heart disease or a history of heart attack
  • high blood pressure
  • overactive thyroid; or
  • a stomach ulcer.

FDA pregnancy category C. It is not known whether COPD is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

COPD can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take COPD?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Always ask a doctor before giving cough or cold medicine to a child.Death can occur from the misuse of cough or cold medicine in very young children.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Take COPD with food if it upsets your stomach.

Measure the liquid form of COPD with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using COPD.

Store COPD at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do nottake extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, thirst, sweating, fast or slow heart rate, ringing in your ears, feeling anxious or irritable, and seizure (convulsions).

What should I avoid while taking COPD?

Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. Guaifenesin is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much guaifenesin. Read the label of any other medicine you are using to see if it contains guaifenesin.

What are the possible side effects of COPD?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fast, pounding, or uneven heartbeats
  • rapid breathing
  • muscle twitching
  • feeling like you might pass out
  • seizure (convulsions); or
  • extreme thirst with headache, nausea, vomiting, and weakness.

Less serious side effects may include:

  • headache
  • mild nausea, vomiting, or stomach pain
  • feeling restless, agitated, or irritable
  • sleep problems (insomnia); or
  • warmth, redness, or tingly feeling under your skin.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect COPD ?

The following drugs can interact with COPD. Tell your doctor if you are using any of these:

  • probenecid (Benemid)
  • aminophylline (Phyllocontin, Truphylline); or
  • theophylline (Elixophyllin, Theo-24, Uniphyl).

This list is not complete and there may be other drugs that can interact with COPD. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about COPD.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.