Chlorphen



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Generic Name: chlorpheniramine
(KLOR fen IR a meen)

What is Chlorphen?

Chlorphen is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Chlorphen is used to treat sneezing, itching, watery eyes, and runny nose caused by allergies or the common cold.

Chlorphen may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Chlorphen?

Do not take this medication if you are allergic to Chlorphen.

Ask a doctor or pharmacist about using Chlorphen if you have glaucoma, a stomach ulcer, severe constipation, kidney disease, urination problems, an enlarged prostate, or a thyroid disorder.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Chlorphen can decrease perspiration and you may be more prone to heat stroke.

Chlorphen can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of Chlorphen.

Who should not take Chlorphen?

Do not take this medication if you are allergic to Chlorphen.

Ask a doctor or pharmacist about using Chlorphen if you have:

  • glaucoma
  • a stomach ulcer
  • severe constipation
  • kidney disease
  • urination problems or an enlarged prostate; or
  • a thyroid disorder.

FDA pregnancy category B. Chlorphen is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Chlorphen can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medication.

How should I take Chlorphen?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medication with a full glass of water.

Take Chlorphen with food or milk if it upsets your stomach.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store Chlorphen at room temperature away from moisture and heat.

What happens if I miss a dose?

Since Chlorphen is usually taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Chlorphen?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Chlorphen can decrease perspiration and you may be more prone to heat stroke.

Chlorphen can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of Chlorphen.

What are the possible side effects of Chlorphen?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking Chlorphen and call your doctor at once if you have a serious side effect such as:

  • urinating less than usual or not at all
  • confusion, extreme drowsiness
  • severe dizziness, anxiety, restless feeling, nervousness; or
  • weak or shallow breathing.

Less serious side effects may include:

  • mild dizziness, drowsiness
  • blurred vision
  • dry mouth
  • nausea, stomach pain, constipation
  • problems with memory or concentration; or
  • restlessness or excitability (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Chlorphen?

Other cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by Chlorphen. Tell your doctor if you regularly use any of these medicines.

The following drugs can interact with Chlorphen. Tell your doctor if you are using any of these:

  • an antidepressant
  • a diuretic (water pill)
  • glycopyrrolate (Robinul)
  • mepenzolate (Cantil)
  • aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others)
  • atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop)
  • bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva)
  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate)
  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or
  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

This list is not complete and there may be other drugs that can interact with Chlorphen. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about Chlorphen.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.