AMBI 1000/5
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Generic Name: carbetapentane and guaifenesin
( kar BET a PEN tane, and gwye FEN e sin)
What is AMBI 1000/5?
Carbetapentane is a cough suppressant. It affects the signals in the brain that trigger cough reflex.
Guaifenesin is an expectorant. It helps loosen mucus congestion in your chest and throat, making it easier to cough out through your mouth.
The combination of AMBI 1000/5 is used to treat stuffy nose, cough, and chest congestion caused by the common cold or flu.
This medication will not treat a cough that is caused by smoking, asthma, or emphysema.
AMBI 1000/5 may also be used to treat other conditions not listed in this medication guide.
What is the most important information I should know about AMBI 1000/5?
You should not use this medication if you are allergic to carbetapentane or guaifenesin.
Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.
Before you take AMBI 1000/5, tell your doctor if you have asthma or other breathing disorder, heart disease, high blood pressure, glaucoma, diabetes, urination problems, an overactive thyroid, or if you are allergic to any drugs or foods.
Also tell your doctor about all other medications you use.
This medication can cause side effects that may cause drowsiness, dizziness, or blurred vision. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Talk with your doctor if your symptoms do not improve after 7 days of taking this medication. Call your doctor any time if your symptoms get worse or if you also have a fever, headache, or skin rash.
What should I discuss with my health care provider before taking AMBI 1000/5?
Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take a cough or cold medicine before the MAO inhibitor has cleared from your body.
You should not use this medication if you are allergic to carbetapentane or guaifenesin.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take AMBI 1000/5, tell your doctor if you are allergic to any drugs or foods, or if you have:
- asthma, emphysema, or other breathing problems
- heart disease or high blood pressure
- glaucoma
- diabetes
- an enlarged prostate or urination problems; or
- overactive thyroid.
FDA pregnancy category C. It is not known whether this medication is harmful to an unborn baby. Before taking AMBI 1000/5, tell your doctor if you are pregnant or plan to become pregnant during treatment.
This medication can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Artificially-sweetened liquid forms of cold medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.
How should I take AMBI 1000/5?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Cold medicine is usually taken for only a short time until your symptoms clear up.
Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Take this medication with a full glass of water. Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
You may take this medication with or without food. Taking it with food or milk may decrease stomach upset.
Measure the liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not crush, chew or break an extended-release tablet. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.
Talk with your doctor if your symptoms do not improve after 7 days of taking this medication. Call your doctor any time if your symptoms get worse or if you also have a fever, headache, or skin rash.
This medication can cause you to have unusual results with medical tests. Tell any doctor who treats you if you have taken a cold medicine within the past few days.
If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.
Store this medication at room temperature away from moisture, heat, and light. Do not allow liquid medicine to freeze.
What happens if I miss a dose?
Since cold or allergy medicine is often taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose can cause confusion, agitation, or restless feeling.
What should I avoid while taking AMBI 1000/5?
This medication can cause side effects that may cause drowsiness, dizziness, or blurred vision. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Avoid drinking alcohol. It can increase some of the side effects of this medication.
Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. Guaifenesin is contained in many combination medicines available over the counter. If you take certain products together you may accidentally take too much guaifenesin. Read the label of any other medicine you are using to see if it contains a guaifenesin.
What are the possible side effects of AMBI 1000/5?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect such as:
- confusion, hallucinations, feeling restless or nervous
- tremors; or
- extreme weakness.
Less serious side effects may include:
- drowsiness, dizziness
- headache
- sleep problems (insomnia); or
- nausea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect AMBI 1000/5?
Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by AMBI 1000/5.
This list is not complete and there may be other drugs that can interact with AMBI 1000/5. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about AMBI 1000/5.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2009 Cerner Multum, Inc. Version: 1.02. Revision Date: 4/12/2009.
